Orgovyx Holiday

Posted by tehill @tehill, Dec 30, 2024

So, I just finished 12 months of Orgovyx and as of today, I begin a Holiday. Of course, how long that lasts depends on when the PSA begins to rise and how quickly. My question is: for those who have gone through this routine; how long (weeks/months) does it take before the side effects begin to diminish, e.g., hot flashes, regain muscle mass and just generally feeling better? Does it really depend on how quickly T goes back up?
Thanks ...

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@rrk25

38 radiation treatments, 6 months on orgovyx ended Nov 30 and I am still having all the side effects. My T is not increasing much at all, was expected to be much higher. Now more testing. If I hear " everyone is different" 1 more time.......

I understand it but I don't like it

Hot flashes, terrible fatigue, memory issues, and most of all muscle loss. I have been doing construction work all though this journey and it is catching up to me now.

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OK, I won’t say it….but I am surprised that your daily physical work has not helped you that much - IF by construction you mean you are digging trenches, lifting heavy pipe, etc all day.
My father was in construction all his life as a sheet metal worker on the jobsite. Mostly in NYC on high rise office buildings. He rose at 4:30AM, would come home exhausted every day, eat dinner and go right to sleep.
Yet, with all that he was no Mr America! Pot belly, no large pecs….but his hands and forearms were scary from cutting that sheet metal with shears I could not even lift!
If he were a foreman or drove a backhoe I’m sure he would have been downright fat (the man could eat and drink!) and in terrible shape. But many days he had to walk up and down 20 or 30 flights of concrete steps because the lift wasn’t operating.
I guess my real question is this: is your construction job involved with burning a lot of calories or giving you an aerobic challenge? I know that sounds absurd and maybe condescending (you’re in construction!!) but I don’t mean it to be.
Just saying that heavy physical exercise really DOES lessen the effects of ADT - even afterwards. So if you’re not really doing the physical work, you really need to exercise at some point during the day - even brisk walking - to raise your metabolism. It worked for me and many others on ADT and that is one way in which we are all NOT that different.

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@heavyphil

OK, I won’t say it….but I am surprised that your daily physical work has not helped you that much - IF by construction you mean you are digging trenches, lifting heavy pipe, etc all day.
My father was in construction all his life as a sheet metal worker on the jobsite. Mostly in NYC on high rise office buildings. He rose at 4:30AM, would come home exhausted every day, eat dinner and go right to sleep.
Yet, with all that he was no Mr America! Pot belly, no large pecs….but his hands and forearms were scary from cutting that sheet metal with shears I could not even lift!
If he were a foreman or drove a backhoe I’m sure he would have been downright fat (the man could eat and drink!) and in terrible shape. But many days he had to walk up and down 20 or 30 flights of concrete steps because the lift wasn’t operating.
I guess my real question is this: is your construction job involved with burning a lot of calories or giving you an aerobic challenge? I know that sounds absurd and maybe condescending (you’re in construction!!) but I don’t mean it to be.
Just saying that heavy physical exercise really DOES lessen the effects of ADT - even afterwards. So if you’re not really doing the physical work, you really need to exercise at some point during the day - even brisk walking - to raise your metabolism. It worked for me and many others on ADT and that is one way in which we are all NOT that different.

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I am a carpenter and I'm 67 do about 4500-5000 steps a day with severe arthritis in both knees. At 67 I got away from the digging part years ago, I make and hang cabinets, drywall, trimwork , exterior trim etc. Lots of bouncing around people houses all day, back and forth to the truck all day

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@rrk25

I am a carpenter and I'm 67 do about 4500-5000 steps a day with severe arthritis in both knees. At 67 I got away from the digging part years ago, I make and hang cabinets, drywall, trimwork , exterior trim etc. Lots of bouncing around people houses all day, back and forth to the truck all day

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Yeah, I have friends in the trades so I know what you mean about bouncing here and there. No way you can sneak in even more exercise given what you do all day. And having arthritic knees (my father needed a double knee replacement at age 72) there’s not much more you can do.
A month off of Orgovyx does not mean you will feel instantly better. They say the side effects after stopping do not take as long to go away as with Lupron but it still may take up to 6 months until your body fully readjusts itself to your ‘old’ normal.
I have heard others complain of the same thing but then report that it started to quickly get better after the first 6 weeks or so. I won’t know myself for about another 30 days; then I am done. But aside from the hot flashes and a voracious appetite, I have not had much in the way of bad side effects as you have had. I did increase my exercise to daily walking, cycling and some weights, but at age 70 I am retired and have the time for it. You, unfortunately, are still working - doing heavy physical work - so it really is hard for you right now.
All I can do is encourage you to not put a time limit on when you should start feeling like your old self - it’s like watching that proverbial pot of water coming to a boil! It WILL happen and when it does you’ll know it! Gotta be better in 2025, right?

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