The typical recommendation is to eat a low fat diet and smaller, more frequent meals to make this condition more manageable. I was diagnosed with EPI along with Collagenous Colitis in the Fall of 2023 and take Creon for the EPI. I don't know how the dosing for Zenpep works, but with Creon I take two capsules with each meal: one with the first bite and the second about halfway through my meal. Creon (along with the Budesonide I continue to take for the colitis) has been a total game-changer and I am able to live a mostly normal life - although I do have to be careful about what I eat.