@mayo4
Did you have any relief from numbness after stopping B6?
Jake

Burning, tingling and slight numbness all ceased

Good morning, @mayo4, @pinoaktree

As you say, what works for some, may not work for others. My experience with B6, guided by my neurologist, has had all to do with distinguishing between the two kinds of B6: pyridoxine hydrochloride, the so-called "bad" kind, and pyridoxal phosphate, the so-called "good" kind. All I can offer is my own experience as testimony. I was diagnosed with idiopathic large-fiber polyneuropathy (no pain, but poor balance) by EMG in August 2022, a condition (I'm guessing) I'd had for 10 years or more at the time of the EMG. The neurologist (not right away, but a few months after) advised that I avoid all supplements containing B6 (pyridoxine hydrochloride) (what I'd be getting in food would be minuscule and not to be concerned about) and stick strictly to the "good" kind of B6 (pyridoxal phosphate), found in certain "medicinal foods." He prescribed a particular medicinal food (which one, because I'm not a doctor, I won't name), and after a second EMG in November 2023 and the medicinal food's use to this day, I'm able to report (about myself only!) that my neuropathy has not progressed (not worsened); it hasn't vanished, but it has not progressed, and that's both a pleasant surprise and something for which I'm very, very grateful. My best to both of you and …

Happy New Year!
Ray (@ray666)

Thank you for your detailed response. My neurologist feels my neuropathy stems from my being treated for rheumaotid arthritis and its affliation. The higher levels of B6 showed up in blood tests. I will have to back track to see which B6 was included in my mega vitamin meds and take it from there.

I am without a practicing neurologist at present so I am just coasting and seeing what is out there that has been successful for others.

Hope we all have a healthy 2025.