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← Return to Anyone on Alendronate?
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I was placed on Alendronate by my Physician due to a Bone Density scan that showed high risk for hip fractures, and within about 3 months, I felt really terrible. So nauseated, could not eat, and lost about ten pounds. Then appetite improved some, but I developed severe pain in my joints. I actually felt like my legs were not attached to my spine, and I was going to fall when I got up to walk. So I went from biking, and running on my treadmill, to severe joint pain. and loss of mobilization. I quit the drug, as it was horrible side effects for me. So now she wants to start me on prolia injections every 6 mo. Guess what-side effects are listed about the same. I am thinking of taking my chances with no drug, but I am afraid she will think I am a non-compliant Pt. Anyone have bad side effects as this?
Replies to "I was placed on Alendronate by my Physician due to a Bone Density scan that showed..."
Hi, I was diagnosed with osteoporosis several years ago and tried all the more natural approaches. In my late sixties and very active and healthy. I finally agreed to do Evenity which I have posted about earlier as I had terrible adverse effects. I went from active and zero aches/pains to after 6-7 months on Evenity felt like I had arthritis and was painful to move especially in the morning. I pushed through for 11 mos then quit as I was done dealing with pain but had excellent gains in my spine. I will be two years out from Evenity in February and most of muscle/bone/joint pain has resolved. However, I was put on Fosomax within a month or two of completion of Evenity and pain got really bad again. Switched to monthly Risedronate and have minimal pain but for me these drugs affect my muscles/joints. I won't have another DEXA scan until September 2025 so not even sure how much it is working but am walking/biking (stopped running) and doing some weight training. My best to you and you know your body best so listen to the medical professionals but don't let them tell you that no one has pain from these drugs or make you feel like you are the first one to have adverse reactions.
Look into AlgaeCal bone building pack. It's all natural calcium from the sea. I've used it for 2 years after which, my spine density improved from -3.2 to -2.7. It is on the expensive side but I chose to spend my money on me instead of leaving it in a will.
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I'd recommend getting a referral to an endocrinologist or rheumatologist to discuss your options. Prolia comes with a savage rebound effect where if you stop the medication you begin to lose bone very quickly. It must be followed up with another bisphosphonate and if you can't tolerate alendronate you'll have to have Reclast infusions (zolendronic acid) regularly and even those can't completely stop the bone loss that comes with Prolia rebound.
This recently published study discusses the outcome of using zolendronate after Prolia: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825942