I experience headaches (on top of chronic daily migraine which I've had for over 20 years), fatigue, brain fog/mild cognitive impairment, muscle and joint pain, persistent cough. I'm only 49 and was relatively healthy prior to LC/PCVS except for back issues and migraines, but the last nearly 4.5 years have been progressively terrible. I am now on short term disability from work--a job I love--which is leading to depression and thoughts of worthlessness. I started seeing a psychiatrist and therapist to help cope with this as my life seems as if it is being redefined by this syndrome. The antidepressant has helped my mood but the cognitive impairment is the worst thing, it gets progressively worse the more fatigued I am.