If he turns out to have BRCA1 or BRCA2 then there is a drug he can use called a PARP Inhibitor that can give more time when Lupron and Zytiga stop working. If He has somatic testing done it can also find BRCA1 or BRCA2 in his blood or tissue and a PARP Inhibitor can be used in that case too.

They even have a drug called Akeega that includes abiraterone and a PARP Inhibitor in a single pill. That might interest his doctor with his having a Gleason nine.