@mimi1234 I had an eGFR in the 50's for years and it was not an issue. I think it is unfortunate that they call it "kidney disease" and even worse, "stage 3." Your creatinine is normal so wondering why your eGFR is 52 (which isn't too bad according to my doctors when mine is at that level).

With eGFR's in the 30's and 40's I do not have any treatment, no. I see the nephrologist once a year. My Cystatin C's are higher and the nephrologist said the truth is somewhere in the middle. I avoid NSAIS's and other meds or supplements that affect the kidneys.

I have lupus and high antibodies for scleroderma so there was some concern about an autoimmune attack on my kidneys since there was a sudden drop, but things are stable. My heart function was checked because that can be relevant to filtration rate, as well as low blood pressure.

Because I have low blood pressure the diet suggested for me is a lot of protein and enough salt, which is very different from most people with kidney disease. I believe muscle loss is another factor for me and protein helps with that.