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The lowest effective dose, how is it defined?
Polymyalgia Rheumatica (PMR) | Last Active: Dec 30, 2024 | Replies (61)Comment receiving replies
"The medical mob now says the physiological dose is around 5mg (4-6) rather than the previous estimation of 7-8, but cortisol levels for individuals vary."
Whatever the physiological dose is, my endocrinologist said I needed to be on "significantly less" to coax my adrenals to respond to a cortisol shortage. I also had to maintain that dose for an "extended period of time." There was no other way.
It wasn't a pleasant year but I didn't have a PMR flare.
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Yes, I understand you had issues with low adrenal function after taking various doses of prednisone for 12 years or so, so what you've done was right for you. There are lots of variables in the lives of individuals. At this stage I have no evidence of adrenal insufficiency, so will keep to the same plan for now.