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Onward with durable remission

Prostate Cancer | Last Active: Jan 2 8:02pm | Replies (37)

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@jeffmarc

Here is one article I found just searching for your question.
https://pubmed.ncbi.nlm.nih.gov/17171704/
I did a search for this “undetectable PSA still have metastasis” And found numerous articles about this problem, Including the one above.

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Replies to "Here is one article I found just searching for your question. https://pubmed.ncbi.nlm.nih.gov/17171704/ I did a search..."

Thanks for sharing that. Just a note that that abstract for that study says it uses data from 1999–2004 for patients with PSA levels from 0.1 to 2.0. As far as I know, those predate the ultrasensitive PSA test (or at least its wide availability). I haven't yet found a study mentioning major metastases with undetectable levels in the uPSA test (< 0.01, or sometimes even lower), but am keeping my eyes open.

Regardless, even for the old data with the less sensitive PSA tests, they were looking at something that happened only very rarely.