@colleenyoung
After decades of various statins reducing my LDL/triglycerides but not sufficiently, and having no improvement on HDL, I was prescribed Repatha. For the first several months it worked! My numbers improved dramatically. Then everything veered southward, horribly so. I read as much medical literature as I could find. I contacted Amgen. One of the nurses answering the help line referenced a study in which a fraction of a percent of people involved in the initial drug trial developed antibodies to Repatha. I'm sadly assuming I must be in this group of unfortunates. Given the $$$ price this med costs, even with insurance, this is very frustrating. I'm at my wit's end. My doctors have no suggestions. Amgen has no suggestions. Btw, when I was first diagnosed with rotten chol/tri, I engaged in a vegan diet for several months. My chol numbers dropped by only six points. So please don't suggest changes to diet - I've already tried that.