← Return to Anyone on Lamotrigine and/or Pramiprexol for Major Depression Disordee

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@louisy

Hi and thank you for your reply. I'm very curious about how you went off of lamotrigine. I have read that it is very difficult and must be done very slowly over a fairly long period of time. Was that true for you? I'm currently taking 150 mg twice a day. I don't know if that's a lot but the shrink told me she has people on much higher doses. I'm just wanting to try to get off of these meds at least one of them. I have no idea what I would feel like without meds. It's encouraging to hear that you're doing better Now that you've discontinued them but I agree that it's something that needs to be done under supervision. Scary stuff right? Our brains are such a mystery and there's so much they don't know but we all do our best. I would love to see what psychiatric care will be like 50 years from now! I figure they will look back on this and think "how barbaric "! Who knows? But again they are doing the best they can with what the research has been able to provide. Thanks again and I look forward to how your experience went.

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Replies to "Hi and thank you for your reply. I'm very curious about how you went off of..."

From my (admittedly sketchy) records, my max dose of Lamotrigine over the 15 or so years I took it (Fall 2009-Spring 2024) was 400mg/day.
Started titrating down from 400mg/day in Fall 2023 as follows (with a few bumps along the way):
60 days@ 200mg/day
30 days@100mg/day
20 days@75mg/day
20 days@ 50mg/day
20 days @ 25mg/day
20 days @ 12.5 mg/day
My logs say my last dose of L was on April 14, 2024. I'd had a nasty itch-like condition that I suspected was L-related but my GP diagnosed it as dermatographia (unrelated to L) and put me on Cetirizine then switched to Fexofenadine, which controls it satisfactorily.
Be advised that I'm retired and a 12-year teetotaler and am no longer subjected to the extreme job stresses and alcohol abuse that I more and more suspect were the primary drivers of my chronic nutjobiness. Like I said before, I really don't think I'm bipolar.
Hope this can be of some help to you.