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Feedback on Linzess for Irritable Bowel-C or Chronic Constipation

Digestive Health | Last Active: Dec 31, 2024 | Replies (169)
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@ghdc

I have UC and recently constipation. My doctor prescribed 145 Linzess. Have taken 3 days (in morning, 30 mins before eating), so far no reaction. Having read other posts I assume that's the norm. It's been 4 days since a miniscule stool using suppository prior to starting Linzess. It's concerning.

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Replies to "I have UC and recently constipation. My doctor prescribed 145 Linzess. Have taken 3 days (in..."
waterlilly | @waterlilly | Dec 27, 2024

Tried all the strengths of Linzess - none worked for me.

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sylvias | @sylvias | Dec 27, 2024

Do you have hypothyroidism? Speaking from personal experience with hypothyroidism I've learn how it causes constipation. Also, for me, it made Mirylax and Linzess useless because it's a motility issue. It slows motility to an absolute crawl which leads to constipation. Once I went on synthroid my gut started to move again. My GI never connected the dots. I also learned that the muscles involved in having a BM get out of sync so they contract instead of relaxing when you try and go. They can be retrained.

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