How do you dial down the dose? I had a severe reaction to my first injection, and when I called the company, my representative said that I should ask the doctor to do a graduated dose to get my body used to the medication. My doctor said she would not do that, and I needed to just use the dose that Was prescribed. I have tried Fosamax, Actonel and Prolia with severe side effects. Prolia caused such severe bone pain I was unable to walk for three months. My bones are so bad. I fractured two vertebrae. Just stretching in bed. Multiple rib fractures toe fracture a wrist fracture and I just have to get my bones repaired so I’m trying really hard to continue to use Tymlos because the doctor said that I would not have the severe bone pain that Paul caused because Prolia such a strong injection so that it last for six months.