I found one case study reporting neuropathy from semaglutide, but that's it: https://pubmed.ncbi.nlm.nih.gov/39072425/. Doesn't mean it can't happen, but it would certainly be unexpected. My neuropathy started when I was ramping up on tirzepatide (zepbound) this summer, but I'm pretty sure that was coincidence rather than causation -- still working through the diagnostic process. Switching from tirzepatide to semaglutide next week, so it will be interesting to see if it has any impact. In my case, I suspect the neuropathy has been essentially latent for many years during which I've taken a ton of neurologically-active drugs for migraines, and emerged when I shifted to a multivitamin with a triggeringly-high dose of vitamin B6 (which happened at the same time as the tirzepatide ramp-up), and may or may not be being helped or hurt by the GLP-1RA at this point. But it's just the guess of someone who is not medically trained, so who knows?