Intermittent Hormone Therapy (IHT): How is it working for you?

Posted by ava11 @ava11, Dec 14, 2024

I thought it is a good idea to have separate thread on Intermittent Hormone Therapy(IHT), so we can all learn from other's experiences.
Who in here are currently on IHT and if you are, please share about your disease specifics and how it is working out for you as much as you can.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@bluegill

I have an appointment with a radiation oncologist in about 3 weeks. My urologist begrudgingly agreed to it.

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Excellent news! You are certainly no newbie, but research as much as you can and write down your questions along with bona fide studies, well known cancer hospital protocols, etc.
If the RO ever looks like a deer in the headlights or dismisses something you feel strongly about, thank him/her for their time and move on to another one.
When I went for my consult at Sloan I had the chief RO - a guy in his 60’s, thought he was a comedian, dismissed my surgeon’s abilities and told me I would need Lupron shots and at least 39 salvage treatments. Moreover, he gave me a prostate exam - “just to be sure” - that almost killed me and he laughed when I screamed….
He subsequently left for Florida ( good riddance!) and my new RO was a wonderful 34 yr old doctor who had co-authored 4 research papers (I Googled him before the visit).
He told me I would be getting the newer protocol of 25 treatments (“only the older guys do 39 or 45 anymore”) and Orgovyx, a newer oral kind of ADT which worked faster, better and let your T come back faster after you were off of it.
I felt that I had entered a time warp! How could two doctors at the same hospital recommend such radically different treatment protocols??
The answer was simple: their age difference….not just the chronological one but the mental one as well. The older guy was just mailing it in, business as usual, my way or the highway; the younger RO was vivacious, really into his profession and had facts, figures and case studies right at his fingertips. I asked a question, he answered and explained why or why not.
I left his office ELATED at needing salvage radiation - how messed up is that?! But he instilled such confidence and hope that now I was all in and no longer feared the treatment.
That’s what I think you have to look for and you will absolutely know it when it happens. Best of luck!
Phil

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@abra990

Hi J Marshall,
My story is similar to yours with a few variations. Surgery in 2009, GS 8, PSA started to rise 4 1/2 years later, had pelvic radiation 2018, long story short, started rising again 2021, 9 months Orgovyx 04/23-12/23, PSA was less than .1 after 2nd month. Off all treatment currently, check PSA every 3 months, latest check October, undetectable. HT was/is no picnic, but tried to stay active and was tolerable. My Dr. at U/Michigan is on board for whatever I want to do, so like you, I know the time will come when more treatment will be necessary, but until then I enjoy every day off treatment. I wish you well and hope we can continue the on IADT program for an extended period. Take care.... Bill.

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Thanks for the reply Bill. At least we have 2 cases where the IADT provides some relief and, yes, let's hope for that extended period! I do think there is good data for our decisions. Good luck!

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