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Tymlos side effects I've encountered

Osteoporosis & Bone Health | Last Active: 10 hours ago | Replies (313)

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@loplady

Can you tell me about this "I took Fosamax for 10 years until growing bone in my jaw "? I just asked my dentist if bone builders like Tymlos, Evenity and Forteo could build any more torrid in my mouth and he thought no, it worked on just bone mass. I also didn't think any bone growth was possible with Fosamax so curious about this.

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Replies to "Can you tell me about this "I took Fosamax for 10 years until growing bone in..."

@loplady bisphosphonates build bone by reducing bone turnover so the bone density increase is not from new bone. Tymlos and Forteo build new bone (filling it in). Evenity does both, new bone first and then it reduces turnover.

Back when I was taking Fosamax, there was no recommendation to stop taking it within a certain number of years. However, cases of thigh bone fractures and bone growing out of the jaw started being publicized. I saw my dentist about the bone growth in my jaw and he said to stop Fosamax. The bone growth did go away. Taking Fosamax for 10 years is no longer recommended.

loplady, Tymlos and Forteo are the most effective medications for torus osteonecrosis which can be difficult to resolve.
Bisphosphonates cause the bone to become avascular (without good blood supply). The bone then is unable to respond to infection and can become necrotic.
Many of us get harmless torus--bone growth in the roof of the mouth and/or under the tongue. Cause is unknown, but grinding of the teeth is suspected as causitive.
The part bisphosphonates play is in the decay and bone death sometimes, though uncommonly, caused in bisphosphonated bone.