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How concerning is this PSA rise?

Prostate Cancer | Last Active: Dec 22, 2024 | Replies (28)

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@ken247

Here is the mri report, am waiting for doctor to contact me to discuss. Please comment if you would like.

Impression
1) Findings suggestive, but not definite, for prostate cancer (score = 3/5). (1 = normal; 5 = highly suspicious).
2) No evidence of extracapsular extension. No evidence of seminal vesicle invasion.
3) Enlarged right internal iliac chain lymph node. No aggressive osseous lesion.
Narrative
Exam: MRI of the Male Pelvis without and with Contrast

History: Elevated prostate specific antigen

Technique: Breath-hold and non-breath-hold multiplanar assessment of the male pelvis was undertaken using external body surface coils to assess extraprostatic disease and stage the pelvis. T1, T2, gradient echo, and steady state images were created, with and/or without fat suppression, per standardized protocol to assess tissue characteristics. These included screening images to assess the abdominal retroperitoneum and regional osseous anatomy for metastatic disease. Multiparametric assessment of the prostate was undertaken with the application of multiplanar T2, diffusion, and dynamic perfusion series in an attempt to characterize intraprostatic disease distribution and volume. Image fusion analysis and semi-quantitative review was conducted using Dyna-CAD prostate imaging analysis software.

IV contrast: 8 mL of Gadovist.

Comparison: None.

FINDINGS:
Prostate volume: 90.1 cc

PSA: 9.8 ng/mL.

PSA density: 0.01

Multiparametric MR evaluation:
Heterogeneous appearance of the central and transition zone, compatible with benign prostatic hyperplasia.

Lesion 1:
Right lateral peripheral zone in the mid gland. Lesion measures 1.4 x 0.6 x 1 cm with a volume of 0.64 cc.

On T2-weighted MR imaging, the lesion is seen as a well-defined focus of low signal intensity (score = 4/5).

The lesion demonstrates mild restricted diffusion (score = 3/5).

No suspicious enhancement identified.

Overall score = 3

Capsular margin and neurovascular bundle: No evidence of macroscopic extracapsular extension.

Seminal vesicles: No evidence of seminal vesicle invasion.

Lymph nodes: Enlarged right internal iliac chain lymph node best seen at series 12, image 5 measuring 1.2 cm in short axis

Bones: No aggressive lesion.

Urinary bladder: Mildly thickened, possibly related to chronic outlet obstruction.

Colon and rectum: Unremarkable.

Other: None.

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Replies to "Here is the mri report, am waiting for doctor to contact me to discuss. Please comment..."

Well, nothing in here says you definitely have cancer. They’re probably going to want to do a biopsy.

A PSMA Pet test might make sense now, it can see if there is any cancer in your body unless it is very small, and that wouldn’t be caught on an MRI either.

A PSE test might be useful in this situation, To maybe be avoid the biopsy because it can tell you if you have cancer. The PSMA pet test might be more useful, however.