← Return to Surgery? Radiation? Can I have an independent suggestion?

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@gently

@hanscasteels,
I would start Orgovyx and continue the indecision with further research knowing that treatment had begun. The optimal amount of time on Orgovyx before surgery or radiation is two months. Even though the drug is expensive, it works by blocking testosterone and synergistically disrupting the dna of the tumor. It shrinks the tumor before surgery and makes it more vulnerable to radiation.
I'd be partial to MRI guided radiation in five fractions. It gives you the closest margins. You won't know with certainty, because no one does--not other patients making the decision, not the oncologists, not the urologists.
Bless your choice.

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Replies to "@hanscasteels, I would start Orgovyx and continue the indecision with further research knowing that treatment had..."

Thank you. I really do appreciate the insight and advise! Sources tell me that, because of past heart folklore, darolutamide (Nubeqa) would be preferred. I'll have that conversation. I'll have the discussion about combining Nubeqa (darolutamide) with radiation therapy and short-term ADT (e.g., Orgovyx or an LHRH agonist), ensuring both local and systemic control.