← Return to Brand Name Cymbalta by Eli Lilly is being discontinued!
DiscussionBrand Name Cymbalta by Eli Lilly is being discontinued!
Depression & Anxiety | Last Active: Dec 22, 2024 | Replies (31)Comment receiving replies
Replies to "I don’t know what else to do. I called the FDA, they couldn’t care less. I..."
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An update on my travails with duloxetine. I've tried a few different things to make it 'work' - it was a horrible experience taking the drug with reasonable expectations that it would be a seamless transition to go from Cymbalta (60 mg) to a generic (60 mg). I tried 3 generics, TEVA, SANDOZ, ACCEL (Montreal Co.). TEVA was the worst, the 60 mg capsule it made me hyper, jittery, anxious, angry. I had high hopes for SANDOZ as its a well known drug maker in Switzerland. It was far better than the TEVA concoction, but it was also making me angry late in the day (generic road rage while hiding under the steering wheel - after all what can an octogenarian with R Arthritis do if challenged). And ACCEL generic was maybe a little better than SANDOZ generic, perhaps I didn't give it a full chance in my tests.
I then tried to go 'cold turkey' off the ACCEL because it was wreaking havoc at 60 mg. After 8 days, 3 days that were easy, and 5 days that were difficult, as it made me want to vomit (never did though), I realized I desperately needed to taper out of duloxetine, rather than go cold turkey. I was a mess.
Here's what I did next. I had my doc prescribe the 30 mg capsules of the ACCEL duloxetine, thinking I could taper out from the 30 mg level since after 8 days of cold turkey, some of the duloxetine would be out of my system. As of today, I'm in my third day of 30 mg duloxetine taken at 8 am each day. Lo and behold, the 30 mg has stabilized me and has given me hope that 30 mg is the dose that can potentially be a reasonable, side-effect free substitute for the 60 mg Cymbalta. It's not a perfect replacement for Cymbalta 60mg, but close enough, at least so it seems after only 3 days on the ACCEL 30 mg duloxetine. I do not get the truly horrendous crazy mental and physical side effect fluctuations I was getting from the much larger capsule of ACCEL duloxetine 60mg.
For now, I can only suggest that you replace the generic Cymbalta that you've been trying at a (significantly) lower dosage, and start from there. It may be all you'll need. If not, try half-dose in the morning, maybe half-dose at bedtime. If it doesn't work, perhaps you could try the SANDOZ brand of duloxetine. Although I'm not presently using it, SANDOZ the pharmaceutical company has a good reputation, has been around for a long time.
I will keep abreast of all the comments here, hoping for some positive outcomes for you all. It's a damn shame that Eli Lily didn't exit the Cymbalta production with suggestions for physicians as to how best to replace their medication. Bloody hell!
If it's due to the timed release properties of the generic vs name brand maybe Eli Lilly share their info.
Duloxetine has the brand names: Cymbalta, Drizalma Sprinkle, Irenka
Are the other 3 available and do they work the same?