ken247:
One other test you could request to have done now in parallel with the MRI and possible biopsy is one of the new urine based tests that look for biomarkers that indicate prostate cancer. I had a stable PSA and normal DRE but requested one of these tests from a urologist just to make sure that I did not have prostate cancer. I was given the ExoDx test (there are other tests besides this one and all seem to be excellent) and the result came back elevated and indicative of a 36% chance of treatable prostate cancer. An MRI a month later was completely clear but my urologist recommended a saturation biopsy 'just to make sure'. Two of the 24 cores indicated a very small percentage of aggressive cancer that required surgery for treatment. I am very grateful for the development of tests like the ExoDx test that provide another screening mechanism to potentially detect prostate cancer very early and when more conventional screening might suggest the absence of cancer.