Connect
← Return to Anyone know if tamoxifen is more harmful than aromatase inhibitors?
Discussion
Anyone know if tamoxifen is more harmful than aromatase inhibitors?
Breast Cancer | Last Active: 6 days ago | Replies (7)Comment receiving replies
Thanks. But my question is a little different. I do not mean how to work for two kinds of medcines for premenopausal and menopausal women.
What I mean: both medicine may have effects, for example:
Tamoxifen make cause uterine cancer, anastrozole or letrozole may led to osteoporosis
That is just some examples , may be there are other effects.
Generally speaking, which kind of medcine is more harmful? that is my question?
Between Tamoxifen (block hormones binding acceptor) and anastrozole or letrozole (stop the body from making estrogen).
For manopause woman, they always has been changed into aromatase inhibitors, alought they can continue to use tamaxifen. THAT MEANS MORE HARMFUL.
Replies to "Thanks. But my question is a little different. I do not mean how to work for..."
Connect
@vickee that is hard to answer. It depends on age and what your preference is. It's like comparing apples and oranges. AI's are considered more effective so some women who are younger, suppress ovaries so they can take an AI.
Side effect lists are on drugs.com. Experiences vary. I was more interested in what was most effective and did an aromatase inhibitor despite already having osteoporosis. People on AI's usually do Reclast or Zometa to protect bones.
If you are post menopausal did your doctor want you on an AI?
It is your choice. But I tried to focus on the positive- stopping cancer- rather than the negative- possible harms. I am not aware of any harms I suffered on an AI other than bone loss. But others have pain. You can always try switching to another AI, switching manufacturers or ultimately switching to tamoxifen if an AI doesn't work for you.