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Anyone know if tamoxifen is more harmful than aromatase inhibitors?

Breast Cancer | Last Active: 6 days ago | Replies (7)
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@colleenyoung

@vickee, I believe you're asking which hormone treatments that reduce the risk of breast cancer returning may have side effects.

Hormone therapy for breast cancer is a treatment for breast cancers that are sensitive to hormones. These drugs can also be used for people who are at high risk of breast cancer to improve the odds of staying cancer-free — an approach known as chemoprevention or preventive therapy.

Here are two articles from Mayo Clinic that list the different medications, including:
- Medicines that block hormones from attaching to cancer cells, such as tamoxifen, toremifene (Fareston), fulvestrant (Faslodex)
- Medicines that stop the body from making estrogen, such as anastrozole (Arimidex). exemestane (Aromasin), letrozole (Femara).
- Treatments to stop ovarian function in premenopausal women
- Combining targeted therapy with hormone therapies

Also listed are the risks or side effects of each of the medications. As with most medications, there may be side effects. Not all people experience side effects. Sometimes they can be manageable. But sometimes the side effects can affect quality of life negatively.

@vickee, which treatment options have been discussed for you?

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Replies to "@vickee, I believe you're asking which hormone treatments that reduce the risk of breast cancer returning..."
vickee | @vickee | 6 days ago

Thanks. But my question is a little different. I do not mean how to work for two kinds of medcines for premenopausal and menopausal women.
What I mean: both medicine may have effects, for example:
Tamoxifen make cause uterine cancer, anastrozole or letrozole may led to osteoporosis
That is just some examples , may be there are other effects.
Generally speaking, which kind of medcine is more harmful? that is my question?
Between Tamoxifen (block hormones binding acceptor) and anastrozole or letrozole (stop the body from making estrogen).
For manopause woman, they always has been changed into aromatase inhibitors, alought they can continue to use tamaxifen. THAT MEANS MORE HARMFUL.

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