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Polymyalgia Rheumatica (PMR) | Last Active: 53 minutes ago | Replies (38)
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Replies to "There was someone on here who said that a nurse told her that tablets should not..."
I don't think the reason is the even distribution of ingredients, no. But the rule of thumb is that a scored pill is fine to split and an unscored pill may not be.
For example, my 5mg Apixaban pills are not scored and a googlesearch said they can be split, but the second half has to be discarded if not used within 24 hours of cutting because the second half may lose strength after exposure to air.
From Drugs.com:
Pills with no line in the middle
In general, do NOT split tablets that are not scored unless your doctor or pharmacist has given you the okay to do this. Some tablets may be extended-release, enteric-coated or have other characteristics that might affect how the tablet is absorbed or works if you cut it in half.