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Esophageal Cancer | Last Active: Dec 16 9:12am | Replies (5)
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Replies to "Thank you for explaining all this. Do you know why it’s difficult to spot in early..."
It's a matter of cell numbers detected in the analysis of the biopsy. Often in early phases of the disease signet cells are not a majority of the dysplastic cells that may appear in the biopsies. It's also dependent upon obtaining biopsy samples from areas of the tumor or nodes that may be enriched for signet cells.