YES I have! I just started Tymlos 12/12/2024 this week. TH and Friday were fine. But, Tonight [Sun PM], and yesterday [Sat AM]...after taking my shot I had a bad reaction. It felt like a burst of pain hit the small of my back then pulsated up my spine quickly toward my head....shooting off toward my heart causing sharp pain briefly there, while the pulse continued up my spine to my head where I got an immediate strong headache. The pulse and pain stopped elsewhere, and just stayed in my head 15-30 minutes, then that pain was done. Scary.
Note. In each case, I did not have the symptoms until after the shot, I made a quick, brief few bits of exertion. First time... I bent over and played with my dog for 30 seconds. The next day, I merely stood up, went into the kitchen then back to my chair. [10-12 steps] After each bit of exertion, is when the symptoms occurred.