@jheieck Recent UK data (2020) concerning over 2500 patients over 45 years of age, investigated patients receiving Prolia “on-time” (at 6 months after their last injection), after a “short-delay” (1-4 months later receiving their Prolia) and those with a “prolonged-delay” (4-6 months later receiving Prolia). It was found that there were 27 fractures per thousand patients in the on time group, 32/1000 in the short delay group and 42/1000 in the prolonged delay group. This clearly demonstrates that the Prolia injection should not be unduly delayed after extractions as the likelihood of fractures is worse the longer the drug is withheld. The extractions for Prolia patients should therefore take place near the end of the 6 months after Prolia was last administered and ideally 2-3 weeks before the 6 month point so that adequate healing may take place before the next Prolia is given.
https://nqsurgicaldentistry.com.au/prolia-the-dental-significance-ph-70/#:~:text=The%20optimal%20time%20for%20any,longer%20the%20drug%20is%20withheld.
This from a dental surgeon's office. I havent located the 2020 study.
There is an ongoing study about the length of time you can remain on Prolia. Every year of the study extends the positive duration. I think it is at ten years now, because the length of the study has reached ten years.