Is 112.5mg Tramadol safe to take with 10mg Cyclobenzaprine?

Posted by eternity @eternity, Dec 9, 2024

Dr. prescribed (3) 75mg Tramadol (112.5mg) for chronic pain at night for sleeping, then 10mg Cyclobenzaprine to combat severe leg/foot cramps with it. Is this posing any risk at all to an 86 year old woman? I took them together for two nights and noticed no improvement in cramped muscles. I've stopped taking the Cyclobenzaprine when they are not effective and there are toxins in every medication. Trying to find out if the risks outweigh the benefits (no change), but possibly needed to take them longer? Not a pill fan, so am I being too careful?

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@bebold

Tramedol is black box contra indicated for us seniors. Known to cause confusion and can actually cause seizures!
I take 50 at a time, up to three times a day with CRPS. But as a retired nurse, I rarely take 3 and know its not incredibly safe taking 2/day with some of my other meds but my pcp is aware and everything is liw dose. J turn 70 in 5 weeks. And this kind of isn't dven totally about age as to mixing safety but side effects are worse after a certain age.

It used to be our pharmacists would question dr drug orders. Not anymore. Maybe call the poison control center and ask. They will know if there is danger mixing them I think. They will refer you to your dr but you aren't asking for personal medical advise, just the facts.

Take goif care. You are right to ask as a senior. We don't want or need a dr not paying attention to destroy our independence at this point. Confused seniors don't get treated well even if its potentially short term and a drug reaction.

Can yoh see a gerontologist. They specialize in the special care of seniors. If it's two different doctors who ordered these meds, this is why we need to not have different doctors ordering medication without checking with each other. B

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Strongly recommend you discuss this you the pharmacist and/or the prescribing doctor.

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@kenc

Strongly recommend you discuss this you the pharmacist and/or the prescribing doctor.

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Oh. Not me. I was responding to the OP about medication interactions. I take low dose tramedol right now, only recently, because I fell last March and tore the labrum in my hip. I need a replacement but it even took 6 mos to get a dx. And will be maybe another 8 months before Mayo can get me in for a hip replacement.

Please check the Original post? As a nurse, I was instructing her of the dangers of a higher dose tramedol for seniors.

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@marquis113

I have one from Boston scientifics. It has helped somewhat. Does not relieve all my ain but seems to reduce it. They have you do a trial first before installing the permanent one. I have had no issues with it. You have to try adjusting the settings a few times before you get relief. I also had multiple injections, nerve ablation with no relief. Also had two failed back surgeries that caused neuropathy and one where the surgeon put the hardware in wrong and I have pinched nerves. Told by three doctors to live with it.

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I’m so sorry that happened to you. No one should be told to just “Live with it”? Telling someone in pain to just live with it is devastating and depressing and can cause hopelessness.
I try to find the best and most supportive provider by asking people I know and trust or through our big teaching hospital in Portland, OR.
Thanks for sharing your experience with the pain stimulator. I’m holding off until I have an MRI on my knee (possible meniscus tear) and back (degenerative disc disease and rupture causing sciatica).
I hope you find relief for the neuropathy and the pinched nerves.
One day and one provider and test at a time!

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I would assume your doctor knows this answer, but you can double-check with your pharmacist.

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@eternity

FYI I take 225 mg Tramadol and it is very effective in easing pain through the night so I can sleep. But I findv10mg of Cyclobenzaprine totally ineffective in easing my muscle crampongvandb10mg is a strong dose. Due to the warning against this combination and the dosages I will not take cyclobenzaprine at all.

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Cyclonenzaprine is a useless pill it helps with nothing

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I am currently taking 100 mg of tramadol three times daily. Three 75 mg tabs is 225 mg of tramadol, not 112. This seems a bit high, but I hope your doc knows what he/she is doing. I take so many other drugs, I have almost lost track. When I look at the conglomeration of pills that I lay out during the day, it almost scares me. I'd like to think that at least one of my four or five docs would mention something if there was a problem. Of course, in this relatively small town here in Delaware, health care is like a vast waste land compared to my previous medical services back in PA.

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@heisenberg34

I am currently taking 100 mg of tramadol three times daily. Three 75 mg tabs is 225 mg of tramadol, not 112. This seems a bit high, but I hope your doc knows what he/she is doing. I take so many other drugs, I have almost lost track. When I look at the conglomeration of pills that I lay out during the day, it almost scares me. I'd like to think that at least one of my four or five docs would mention something if there was a problem. Of course, in this relatively small town here in Delaware, health care is like a vast waste land compared to my previous medical services back in PA.

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I appreciate your comments and sp agree with the loss of healthcare it's the same in Ontario. As for speaking to doctors about med combinations that are safe, I've found in our city that our pharmacists are easier to get ahold of and are right on top of this topic. Give them a try and good luck.

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Both Tramadol and Cyclobenzaprine increase serotonin levels and it is recommended to find alternate drugs. If you’re a senior cyclobenzaprine can be problematic for us, please be cautious.

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@jenatsky

Both Tramadol and Cyclobenzaprine increase serotonin levels and it is recommended to find alternate drugs. If you’re a senior cyclobenzaprine can be problematic for us, please be cautious.

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Thank you for saying that. It confirms what I have found online and been told by others. Very concerning that it is my doctor that gave it tome, and I need to correct my math. Three 75mg Tramadol is 225mg taken at night (that he prescribed, then added a strong 10mg Cyclabenzaprine.
I'm grateful for this Mayo Clinic connect, as it is giving me what I need, when my doctor is doing the opposite. Thank you very much

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