bay area58, I did not take antibiotics. I rely on nebulizing and mucinex twice daily, and a vibrating vest and postural drainage every day. It is time consuming, but I feel like I am living a pretty good life for a 76 year old. Travel a bit, take care of my chores without outside help, pursue friendships and hobbies, and get a couple of good walks with the dog each day. I"m not sure what else I could ask for.