After posting my question here, I found a thread at inspire.com, evidently the message board for the "ZERO Prostate Cancer Support Community", titled, "Orgovyx Side effects and when they kick in".
This search should take you there if interested: "site:inspire.com Orgovyx Side effects and when they kick in"

My take from the messages there and the very helpful replies I received here is that the odds are very good I'd be fine to start the Orgovyx ahead of my trip, recognizing that everyone is different in their side effects, both in whether and when they show up.

I am inspired to increase my exercise regimen, as the benefit from that is the one very consistent message throughout.

Thanks heavyphil, akiwi, toolbelt, and callibaetis---best to you all.