Welcome to Connect @jojo2059 . It has to be heart wrenching to see your brother going through so many health issues. My husband had high grade bladder cancer diagnosed 5 years ago. He has had multiple surgeries and did have chemo with Cisplatin after the first surgery. He was recommended to have a port and that worked well for him. It was removed around a year after treatment. Your brother needs help in making the decisions about treatment, but ultimately it is his decision unless he is declared mentally incompetent. Has he had neurologic testing for his potential dementia?