Intraductal Prostate Cancer: Any info about recurrence rates?
Anyone on here have intraductal prostate cancer and low Gleason? I was diagnosed this year and had surgery. Gleason 3+4 and clear pathology except intraductal. Doctors just say follow up PSAs which have been thankfully, undetectable. However I am not understanding future reoccurrence rate and which medications/treatments I will need. Anyone on this forum with intraductal?
Interested in more discussions like this? Go to the Prostate Cancer Support Group.
( sorry @jeffmarc, Imeant to reply to the OP)
There seem to be 2 types of IDC-P, pattern 1 and pattern 2.
One had a very similar prognosis (for the treatment given in the study) to normal PCa the other was more aggressive. The less aggressive variant was less common: 25-30%.
Can provide a link if you are interested.
I tried asking my urologist what type I have but he got no answer from the pathologist! I will ask for a second opinion from another pathologist.
I decided to add Abiraterone to my ADT because of the aggressive disease.
I am also cT3b N0M0 based on PET PSMA.
I also have quite a few studies I've collected but they are a bit depressing. 🙁
Just something to think about. If you are on Lupron or Orgovyx Or equivalent and it takes your PSA down to undetectable you may not want to start anything else. Because it can reduce the amount of time that you can stay undetectable or close to it.
I was able to go 2 1/2 years on Lupron before it failed and I became castrate resistant. I then started Zytiga And for 2 1/2 more years, it kept my cancer under control. The combination of drugs, so early may not be beneficial, It’s really hard to say
I’ve been on Darolutamide For almost a year and a half, and it’s kept my cancer undetectable. Getting 2 1/2 years out of Zytiga Was well worth it.
If your cancer has spread, and you have multiple metastasis, then maybe you want to use Triple therapy, which includes chemo.
I think things vary from person to person, but take a look at the STAMPEDE study. It seems to say that Abiraterone added to ADT earlier improved overall survival and metastasis free survival.
These people started off with a PSA with an average of 53.
I started on Zytiga, but not until after Lupron Failed, and Zytiga gave me 2.5 extra years after that. My PSA was 1.2 when I started Abbie.
The thing is drugs like Zytiga don’t work forever. I had to quit because it caused me heart issues. Other people I know have quit because it failed, and their PSA started rising.
Maybe taking it along with ADT could just be most beneficial when you have a high PSA, or when it is locally advanced or metastatic as the stampede trial says.