Hello, czauderer,
These two ladies are highly knowledgeable. and helpful. There is alot of research out there to examine. I, myself ,have been trying to get off of Prolia after 5 injections. I wanted to do it sooner but was unable to get an endo to assist me. I see a new endo in January and am hoping that he will be willing to work with me about doing this. I had not been informed about the danger of coming off Prolia before going on it. While I haven't had difficulty with it I am very fearful of the rebound effect when coming off of it. Of course the longer you are on it the more challenging it becomes to curtail its rebound action. There is an article by GRASSI, et al entitled Zolendronate aftet Denosumab discontiuation: Is repeated administrations more effective that single infusion. It is a April 13,2024 article. in the Journal of Clinical Endocrinology and Metabolism. You find it helpful to read. Margaret Martin,PT, has a you tube video entitled Long term side effects of Osteoporosis drugs. I found that very interesting and informative. I would recommend that as well. A continued conversation would be welcome. Thank you.