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← Return to Testosterone replacement after radiation and Orgovyx?
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Testosterone replacement after radiation and Orgovyx?
Prostate Cancer | Last Active: 2 days ago | Replies (33)Comment receiving replies
This damned T question is really an enigma. We KNOW if fuels PCa, we KNOW it increases PSA, and we KNOW its absence reduces almost every biomarker associated with prostate cancer.
Yet, why don’t we get cancer in our 20’s or 30’s when T is highest? Why do most get it when their T is actually declining? How does bi-polar therapy really work on a cellular level?
Because the doctors have no answers to these simple questions (well, mine don’t - they chuckle) men will always be confused about this.
I’ve often wondered if any studies have been done on the T of cancer patients vs the T of cancer free patients. I despised organic chemistry, but I did learn that one ATOM or one extra methyl group or saturated bond will completely change the chemical properties of a molecule. Can our T change somehow and actually become the carcinogen or the initiator? My head hurts thinking about these sorts of things but all of us want to know the ‘WHY’ more than anything…
Replies to "This damned T question is really an enigma. We KNOW if fuels PCa, we KNOW it..."
"why don’t we get cancer in our 20’s or 30’s when T is highest?"
Because the testosterone doesn't cause prostate cancer; it just feeds the cancer and helps it spread once it already exists.
Since young men (under 45) almost never develop prostate cancer, their higher testosterone does them no harm, cancer-wise.
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I think it’s more like, over time Errors occur in your DNA, As you get older, your body has a harder time correcting them. As a result, over time you end up getting prostate cancer as the DNA That has changed to prostate cancer starts to grow more of its own friends,. Now if you have BRCA Then it’s even harder for your body to correct the errors and you get it at a younger age.
I think it really does come down to that. Some people are genetically more prone to it, I know 2 guys in another group that each have two brothers and all three got prostate cancer relatively young. In my case, my father got it and so did My brother and I, and he doesn’t have BRCA2. He got it a lot older than I did, 14 years older, Because BRCA2 Accelerates the errors.