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@staylorrn2000

I came to this group hoping to find some info about prednisone withdrawal vs adrenal insufficiency caused by tapering too quickly. I have been put on multiple prednisone bursts over the last 6 months and a couple of courses lasting 3 weeks. All were successful tapers until this last one and now that I’m down to 5 mg daily I am having constant cold clammy skin and cold sweats, also increased fatigue, stomach pain, nausea and dizziness. The doctor had me take 5 mg for 7 days then 2.5 mg for 7 days then off for 2 days to have labs, cortisol and ACTH, both of those came back normal. The whole time I was on the 5 mg daily and 2.5 mg daily I’ve had these symptoms and they have gotten worse since I was off of prednisone for 2 days so I’ve gone back to 5 mg daily with no relief of my symptoms. My question is can you have a normal cortisol and ACTH level and still have adrenal insufficiency? My doctor says no but I’ve read that you can if the pituitary isn’t functioning properly. I also read the only way to rule out adrenal insufficiency is with an ACTH challenge. I certainly don’t want to end up in an adrenal crisis if I have actually do have adrenal insufficiency vs. steroid withdrawal. Any advice anyone can offer will be greatly appreciated. Thanks in advance.

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Replies to "I came to this group hoping to find some info about prednisone withdrawal vs adrenal insufficiency..."

@staylorrn2000, you might find this discussion helpful:
- Adrenal Insufficiency and Tapering Prednisone https://connect.mayoclinic.org/discussion/adrenal-insufficiency-and-tapering-prednisone/

Have you discussed your questions with your doctor or an endocrinologist as @dianekbrown mentioned?