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Anyone had targeted treatment for KRAS G12R, MDM2 and SMAD4 Y412?

Pancreatic Cancer | Last Active: Dec 12 11:46am | Replies (6)
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@gamaryanne

Yes. I am on a clinical trial that includes a combination of drugs. One targets KRAS G12D specifically and the other is “panKRAS” targeting the KRAS family of mutations.
If you have not tried one of the standards of care therapies yet; your doctor can use this information to match you to the one that has the most success shrinking tumors with your particular gene characteristics.
So glad you are at a facility that recommended this. It is very important on this healing journey.

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Replies to "Yes. I am on a clinical trial that includes a combination of drugs. One targets KRAS..."
angeleji2 | @angeleji2 | Dec 11 10:15am

Thanks so much!! Since I've had the whipple surgery, the current plan is to power-wash the micrometasis. I hope there's no tumors to shrink. It's helpful to know about panKRAS. I will do more research on this!! THANK YOU.

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