My reactive arthritis went away after a few months on methotrexate. I did PT and ramped up aerobic/weights afterward the RA was gone. The RA hit me hard in 1989 (I'm now 70 and it didn't recur). Methotrexate works by decreasing your attacking cells. Once the immune response diminished, my RA didn't return. This was 35 years ago so there are newer meds now. Meds like Celebrex and NSAIDs help to decrease inflammation, but their effects are pretty limited (and hard on GI tracts). It is good to talk with a counselor as well. He/she can help with some of the grieving process of illness and with steps going forward to have help. Here are some methotrexate pubs (not always easy to understand): https://www.nature.com/articles/s41584-020-0373-9 https://www.ncbi.nlm.nih.gov/books/NBK556114/#:~:text=The%20most%20common%20adverse%20effects,effect%20of%20methotrexate%20is%20hepatotoxicity.