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Antihistamines for improving BC survival

Breast Cancer | Last Active: 55 minutes ago | Replies (7)
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@lilacs777

Yes very exciting, what I've seen seems to be mostly related to immunotherapy response and cancers that are more immunogenic but I'm hopeful that this may apply to ER+/PR+ as well. Even in hormone cancers, your immune system still has a lot of work to do so hopefully this would help. So far I haven't found anything that antihistamines reduce the effectiveness of AIs or tamoxifen.

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Replies to "Yes very exciting, what I've seen seems to be mostly related to immunotherapy response and cancers..."
lifetraveler | @lifetraveler | Dec 10 7:48am

Thanks for sharing the exciting information and article, @lilacs777 & @triciaot !

This is indeed very exciting research finding; however, according to one article published by Harvard Health Publishing Staff in 2022, it had the following warning:

"A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia... Anticholinergic drugs include some antihistamines, tricyclic antidepressants, medications..."

I am not a healthcare professional, so I have very limited medical knowledge, of course; but I think we need to treat this exciting correlation between taking Antihistamines and BC survival with caution. For as I grow older, I fear the disease of dementia even more than BC:(.

Best wishes to you all!

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