Debbie - I can personally guarantee you that Mayo can't fix all things....I am proof of that. When I went to Mayo in Feb 2020, I did see two neurologists in MN who told me what I have but no idea why. These two neuro docs specialize in PN. Of course, that is my case, and not all cases are the same. I went through a number of tests that 3 other teaching hospitals never did. You are right, not all illnesses have a reason, answer or a cure. We with PN know that well.