← Return to Forteo and weight gain
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Osteoporosis & Bone Health | Last Active: Dec 10, 2024 | Replies (34)
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Replies to "I have been told that there are no indications for weight gain with teriparitide use? I..."
You can find associated information by looking at the effects of hyperparathyroidism on weight gain. Teriparatide's mechanism of action raises the serum levels of parathyroid hormone. High levels of parathyroid claim calcium from our bones, and kidneys and increases absorption from the intestine. but transciently unlike hyperparathyroidism. The loss of calcium in the bone engenders the processes that build bone.
But the increase in serum calcium draws calcium into fat cells. The extra calcium in fat cells prevents them from apoptosis--natural cell death.
In general postmenopausally women collect the most fat cells at the waist hips and thighs and this is where the calcium-happy fat cells become longer lived with both Tymlos and Forteo use.
If a clincal trial questions survey doesn't ask about weight gain, a participant is unlikely to enter information about weight gain. If a prescribed patient mentions weight gain it remains unreported. Instead patients are encouraged to pay closer attention what we eat and how much exercise we are getting. Whether a societal effect or biological, it is easy to get women to blame themselves.
It is recognized that hyperparathyroid patients are commonly more burdened with fat than their cohorts.
Some Forteo patients don't gain girth with the medication, likely because of their calcium status during the four hours of high parathyroid effect with the medication and perhaps a lower base level of normal fat tissue.
With the number of women experiencing the gain, I've not heard of even one of their physicians supporting the claim.
I've been on Forteo for 21 months and have not experienced extra fat. My calcium intake may be lower than optimal for bone growth.