AI's work by eliminating estrogen produced by the adrenals. I would imagine very small amounts of estrogen via vaginal application would counteract an AI to some extent since the goal is "below detectable levels."

Tamoxifen, like raloxifene, shuts down certain estrogen receptors so I guess it would work regardless of the level of estrogen. Good to ask doc!

With my history, I am not going to risk it but wish I could!