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← Return to Discontinuing Prolia (denosumab): How can it be done safely?
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Discontinuing Prolia (denosumab): How can it be done safely?
Osteoporosis & Bone Health | Last Active: Dec 12 1:22pm | Replies (35)Comment receiving replies
@windyshores, you're right that discontinuing Prolia (denosumab) causes a reversal of the drug's potent anti-resorptive effect and this leads to rebound. However, if used indefinitely contnuous use denosumab can be an effective treatment for the chronic lifelong condition of osteoporosis.
For everyone, this study is helpful in answering many of your questions about Prolia (denosumab)
- Discontinuing Denosumab: Can It Be Done Safely? A Review of the Literature https://pmc.ncbi.nlm.nih.gov/articles/PMC9081316/
It addresses many of the issues revisiting in the Osteoporosis Support Group, such as
- What Happens If Denosumab Is Discontinued?
- What Are The Risk Factors For Vertebral Fractures When Denosumab Is Stopped?
- Should Denosumab Be Used Indefinitely?
- When Should Denosumab Be Discontinued?
- How Do We Stop Denosumab Safely?
- What Do Some Of The Guidelines Recommend?
- How Do We Handle Inadvertent Discontinuation Of Denosumab During The Covid-19 Pandemic?
Replies to "@windyshores, you're right that discontinuing Prolia (denosumab) causes a reversal of the drug's potent anti-resorptive effect..."
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Thank you so much for this! I had been on Reclast for several years and my last DEXA did not show any improvements. Thus, my endo and I discussed trying something else. He said that he has seen excellent results with Prolia with a side note that I will be on it for the rest of my life. I had my first Prolia shot and had no side effects. Let’s hope that continues. Had none with Reclast as well. I have never fallen, no fractures, etc.
Everyone seems to be afraid of Prolia. I trust my doctor as he said that he would tell his mother to take it when and if needed. Shopping around for a doctor to get the answers you want because you are reading so many articles is not a good thing. Who is writing the article? Doing the research? There is a ton of misinformation out there!!
When i have any doctor’s appointment, I ask a ton of questions! I am not looking for the answer I want but the reason why a certain drug is recommended for me. I have already done my research before I see the doctor. As i mentioned, you have to be so careful with the research out there and this is coming from someone who was in the healthcare business. I apologize for ranting on and on but people, stop shopping around for doctors to get the drug you think is right for you or for answers you want to hear.