I'm not in a position to address your question. As I posted, the majority of medications and supplements can take a period of time before one can begin to have evidence of results. Again, based on personal knowledge and from past educationas sources, factors vary by person. Info is generally provided online, on medication/supplement inserts. I won't deal with any company that does not provide information/address questions. From personal experience, I know how vexing it can be to have to wait, thinking in the interim "what a waste"...So, sorry, I can not give you an answer. Review the sources that I've suggested checking. I can say this much: 6 months certainly seems like a wide enough window, and I always make notations in a Log. (Great when communicating with members on medical team, and for personal erudition). If you haven't been able to write notes about improvements, (or have negative effects), I'd definitely consider eliminating that item.🤔. This is a great idea with medications, since I can then inform doctors SPECIFICALLY why I will not stay on an especially troublesome medication; same goes for supplements. My new urogynecologist is young and incorporates herbs, etc. for bladder and GYN health, but two herbs in particular were definite No-No's for me, and two others were very contraindicated based on my history. Although a tad miffed, she respected my decisions. I strongly encourage keeping a Medical and a Prescription/Supplements Log. Mine are online, so I can add/delete, and definitely convenient to do a print out when seeing a new doctor. My arthritic fingers thank me, and the office staff is saved from trying to decipher the "writing."😊