1. < Prostate Cancer

Stage 4 Prostate Cancer and Hormone Therapy quit working

Posted by cal77 @cal77, Oct 28 12:48pm

My husband is at Stage 4 for one and a half years now...The hormone therapy (Apalutamide and Erleada) seems to have quit working. For the past 8 months, his PSA keeps climbing. It's up to 12 now..
We're scared. Anyone else got to this point? How are you doing when the hormone therapy isn't working anymore.

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melcanada | @melcanada | 2 days ago
In reply to @cal77 "My husband is otherwise healthy. He's been on Apalutamide and Eligard shots, had several bone scans..." + (show)
@cal77

My husband is otherwise healthy. He's been on Apalutamide and Eligard shots, had several bone scans and CTscans, but no PET scan and hasn't had any radiation or chemo. We see the Oncologist next week. Thank you for your help and prayers

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Ask about % od chance for PSA flair up Also % chance of fluid on lungs Pulmonary edema as well caused by chemo I got both PSA 181 from 40 from10 a year ago

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9036george | @9036george | 1 day ago

I too a stage 4 er (psa856)started with hormones ( lupron and Xtandi) which I’m still taking. Was effective for 9to10. Mos—kept psa in normal range , then went to 86—added a round of chemotherapy—psa been holding about 11—have started round of nuclear therapy.psa still holding. And yes for me to is a scary situation. I try to be grateful for today, hang tight with friends and family, lean on spiritual well-being. Wishing you all the very best.

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jeffmarc | @jeffmarc | 1 day ago
In reply to @9036george "I too a stage 4 er (psa856)started with hormones ( lupron and Xtandi) which I’m still..." + (show)
@9036george

I too a stage 4 er (psa856)started with hormones ( lupron and Xtandi) which I’m still taking. Was effective for 9to10. Mos—kept psa in normal range , then went to 86—added a round of chemotherapy—psa been holding about 11—have started round of nuclear therapy.psa still holding. And yes for me to is a scary situation. I try to be grateful for today, hang tight with friends and family, lean on spiritual well-being. Wishing you all the very best.

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Are you planning to get Pluvicto soon? Yet can reduce the PSA Significantly in about a third of the people that get that treatment And another third get some benefit from it.

11 is still high.

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