Yes! A slow transition to Pepcid and then taper Pepcid, cutting it in half at some point, then not taking it one day a week, then two. Tums can be used to help too. None of this is written in stone. If heartburn is unbearable (it may be strong at first) the taper can be slowed down. This is entirely my method though I have read about it from others on this forum and elsewhere. Doctors in my experience tend to say to just stop, but often heartburn is then so bad (because of the increased acid production with PPI's) that people just stay on them forever. It is possible to get off. PPI's affect absorption of nutrients, I have been told. They can contribute to osteoporosis too.