Withdrawal from orgovyx: How long will fatigue and hot flashes last?

Posted by bobmcr @bobmcr, Oct 12 6:38pm

Having hot flashes and fatigue 2 weeks after stopping orgovyx. Is this to be expected and for how long?

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I'm entering the phase of my treatment as well, and my general research has shown that these side effects are probable to happen until the testosterone levels recover to nearer normal levels.

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@edmond1971

I'm entering the phase of my treatment as well, and my general research has shown that these side effects are probable to happen until the testosterone levels recover to nearer normal levels.

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About how long does that take you think??

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@bobmcr

About how long does that take you think??

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There is probably a study on this, but I think that age plays a role and also the type of ADT you are/were taking. I did an injection of Eligard so it will likely continue to leak into my system for a while. I'm 53 and my health team indicated there it is probable for a modest recovery in 6-15 months.

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@bobmcr

About how long does that take you think??

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This depends on age and luck. The older you are the longer it takes to recover testosterone. One rule of thumb is it takes as long as you were on the drug to recover your testosterone fully. With Orgovyx it usually comes back quicker however.

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I was on Orgovyx for 6 months, and it took about a month for the hot flashes to stop. My pre-treatment T was about 580, one month after completing Orgovyx it was back to the low 400's, from a low of 14.

Stay Strong Brother

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@bobmcr

About how long does that take you think??

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Recovered 80% in 8 mos.
My pretreatment Testosterone was mid 400s (73 yrs old).
4 mos Orgovyx tx; 8 mos post tx mid 300s.
Best wishes.

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@michaelcharles

Recovered 80% in 8 mos.
My pretreatment Testosterone was mid 400s (73 yrs old).
4 mos Orgovyx tx; 8 mos post tx mid 300s.
Best wishes.

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8 months post treatment , what was your PSA?

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@ecurb

8 months post treatment , what was your PSA?

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PSA has tested < .02 after Salvage Treatment of ADT and radiation at 6, 9, 12 & 15 mos following completion of radiation portion in May 2023.
RP primary treatment w/ persistent PSA of .19 resulting in Salvage Treatment.
Very pleased obviously at near term outcomes.
Best to all

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@toolbelt

I was on Orgovyx for 6 months, and it took about a month for the hot flashes to stop. My pre-treatment T was about 580, one month after completing Orgovyx it was back to the low 400's, from a low of 14.

Stay Strong Brother

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Just had my first post Orgovyx T test and, after 5 1/2 weeks, my T is at 360. Glad its recovering so fast. Fortunately, PSA has stayed low at .3 (had radiation in June 2024 as primary treatment).

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@scottbeammeup

Just had my first post Orgovyx T test and, after 5 1/2 weeks, my T is at 360. Glad its recovering so fast. Fortunately, PSA has stayed low at .3 (had radiation in June 2024 as primary treatment).

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Excellent results, congratulations! I think Orgovyx is the way to go.

Stay Strong Brother.

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