Thank you. I have had all of the above elevated for over 2 years, almost 3. My GGT is about 500 or so, maybe not too high but high. Antibodies triple (something there with cytoplasmic staining), and also my M2 was positive. My ESR has been triple, quadruple what it is supposed to be for almost 3 years. The Dr. did nothing. I am pretty sure with those positive outcomes and the numbers, that it is PBC. I have never gotten blood work regularly a all. But I do recall a couple times when I was sick or whatever, some being high and having it brushed off. I had several bouts of pancreatitis over 10 years ago that the Dr. attributed to meds, so I changed and never had again. Gallbladder was removed. That's all why I am a bit nervous. I can't even get a gastro to call me back in this darn city (Syracuse, NY). I've been waiting 2 months on the referral once my Rheum finally decided to do something. So who knows when an appt is going to be. So I took it into my own hands and scheduled with Mayo hepatology.