@marianepp how is anyone "weaned off" Prolia? I have never heard of that and if it is possible, we need to know. Is this doctor suggesting lowering the dose over time? Is this doctor not mentioning doing Reclast to manage rebound? I wonder if this is an endocrinologist. Any info on this would be welcome for all of use I am sure since many of us are avoiding Prolia, which is in fact a potent bone builder. I have just been told it is dicey to stop.

@mariannepp, gosh, breaking 4 ribs must have been painful. I can imagine you are afraid of a hip fracture. Having osteoporosis and being a "faller" or prone to falls puts you at high risk of fracture.

I understand your reluctance to take medication. And you did your due diligence by consulting three doctors. That is important. I think you have your answer. Despite sharing your prescription history, you heard from each of the 3 medical professionals that your health with a life-long condition of osteoporosis needs some help with medication.

I hope you and your doctor can agree on the medication that is right for you. We are lucky that modern medicine has focused on osteoporosis to have discovered several medication options that work well to keep our bones healthy and reduce the risk of fracture. As we know, fractures can be serious and even life-threatening as we age.

@mariannepp, may I ask what makes you prone to falling? Have you worked with an occupational therapist or physical therapist to work on balance and ways to prevent falling?

@mariannepp
I do not know your bone density scores and other pertinent details but I would think a bone builder would be what was called for if I was fracturing like that. Did your doctors discuss that option with you?

@windyshores you might want in on this.
One of your doctors mentioned weaning you off of Prolia as if that is something that they know can be done.
I found one study on this.
It's a study of weaning a 13 people off of Prolia. As they lowered the Prolia doses the bone loses increased. They went from 60mg to 30mg to 15mg. It doesn't look like they got them off Prolia. They say they preserved 40% of the Prolia gains but looks like they are still on Prolia. I believe that approach failed to preserve hip gains? And I do not see any mention of the potential for multiple spinal fractures when stopping Prolia. Only bone loss is being considered. I admit I did not study this paper carefully as I'm staying away from Prolia for the forseeable future.

Here's their summary "To date, no therapeutic protocol using bisphosphonates fully preserves bone gain after Dmab withdrawal. A progressive decrease in treatment preserves 40% of the gain at the spine.
More studies about Dmab tapering are needed and potential usefulness of combining bisphosphonates with low-dose Dmab remains an unexplored area.
Administration of 15 mg of Dmab is sufficient to prevent complete BMD loss and to keep CTX levels low. This approach could be an alternative when bisphosphonates are contraindicated following Dmab."
https://onlinelibrary.wiley.com/doi/full/10.1002/jbm4.10731