My husband has suffered with foot neuropathy, not related to diabetes since he had it YEARS before endocrinologist declared he had Type 2, with AIC always being below 6....Anyway, it has progressed to bouts of intensely painful, burning neuropathic pain which was so bad that he could not get any sleep. He learned online how application of Vick's helped many sufferers, so he tried it. Slathered on the stinky ointment and covered both feet with non binding socks. He found relief, ranging from lessening of pain to PAIN GONE. OVER TIME, THIS HAS NOT WORKED AS WELL AS AT ONSET. His endocrinologist (fairly new of about 3 yrs since the other one moved way far from our area) is receptive and open to anything that works for her patients, and is respectful of my husband's not wanting to take prescription medication (he has a laundry list of medications and supplements for several serious health issues). He does take ALA, and has done so for years, but definitely there are circumstances under which the ALA has not been as effective. However, he continues taking it since overall his neuropathic pain does seem to be held in check by the supplement. Rheumatoid arthritis and Raynaud's have roles in the pain that he deals with. Wears nonbinding, thick socks (with elements of wool) and took my advice of replacing shoes with 1/2 size larger, WIDE width, comfy-padded, and ample foot bed to allow for comfort. No leather, which don't allow for "stretching out" of toes and leather can create pressure over tops of feet.