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ANA Titer 1:1280 pattern homogeneous and speckled o/w negative work-up
Autoimmune Diseases | Last Active: 2 days ago | Replies (42)Comment receiving replies
@larak - Thank you for providing this source. Unfortunately, I am at the mercy of those who provide me with medical treatment. Essentially during the last contact with the clinic the doc asked me do I want pilocarpine or not and it was my choice but kept stating my workup was all normal this referral to ENT and for what I'm not sure but send with the diagnosis of glossitis
Replies to "@larak - Thank you for providing this source. Unfortunately, I am at the mercy of those..."
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Mine all indicate systemic sclerosis. Some indicate Sjogren's or lupus as well. None of my five patterns correlate with the standard antibody testing rheumatologists normally run. (Most of those you listed.) My ANA is also 1:1280. Normal folks can have elevated ANA titers but usually not that high.
My genetic results suggest either Behçet's or systemic sclerosis. My understanding is that it would be rare to have both.
But something is clearly up.
I have high IL-10, IL-6, and IL-2R cytokines and occasionally elevated C3. CRP and ESR are fine, though. I have a positive HLA-B51 antigen test. I also have atopic dermatitis, a 5 cm ascending aortic aneurysm, a dilated pulmonary artery, IBS-C, GERD, hair loss with occasional lesions (follicitis?), and my eyesight is getting worse. Elevated pressures, small cataracts, wicked dry eye, and I'm losing perception in my infranasal region in my right eye on field tests.
I also get mouth sores.
I'm taking pictures of whatever I can now: hair lesions, rashes, mouth sores, red eyes. I'm gathering all my records.
It's insane trying to get an autoimmune/autoinflammatory diagnosis. You really do have to be mid-flare or do all the work yourself, even with an ascending aortic aneurysm.