I have chronic nausea and live on Zofran that dissolves on my tongue. I have many gastro diseases. The generic forms don't work on me they make me vomit. I take 8mg and I take it sometimes every hour. Sometimes I can go several hours. But I can't take it 8 hours apart. Through the year's my gastroenterologist has told me to take it however it will help me. Sometimes it doesn't. Chronic nausea is awful and I pray your husband finds something to take the edge off. Good luck 🙏🙏🙏